ydeL [2019-06-21 08:53:42]

similar to transcriptional regulator ([SW|MocR/ GabR family])

locus: BSU05240

pI: 9.22

mw: 53.36 kDa

protein length: 463 aa

gene length: 1392 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]

Gene

Coordinates: 571,389 572,780

The protein

Protein family

• [SW|MocR/ GabR family ][Pubmed|22020104]
• [SW|class-I pyridoxal-phosphate-dependent aminotransferase family] (according to Swiss-Prot)

[SW|Domains]

• N-terminal DNA-binding helix-turn-helix motif; C-terminal domain is homologous to PLP-binding large domain of aminotransferases.

[SW|Cofactors]

• PLP

Structure

• [PDB|4MGR] ([protein|C7C36FAC0CE72226960FC7E8E016B8EC77AF1036|GabR], 38% identity) [pubmed|24127574]

[SW|Localization]

• nucleoid (Homogeneous) [Pubmed|16479537]

Biological materials

Mutant

• MGNA-C083 (ydeL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2081 NBRP B. subtilis, Japan]
• BKE05240 ([gene|05A23F4611674B0092262DEC309F7AD6B9B5BE30|ydeL]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE05240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCGCGTTGTTCTCCT, downstream forward: _UP4_TGAGGGAGCTTTCAGTTTAG
• BKK05240 ([gene|05A23F4611674B0092262DEC309F7AD6B9B5BE30|ydeL]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK05240 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCGCGTTGTTCTCCT, downstream forward: _UP4_TGAGGGAGCTTTCAGTTTAG

References

• 11756427,16479537,21630458,22020104,24127574